Conflict-of-Interest Guidelines for a Multicenter Clinical Trial of Treatment After Coronary-Artery Bypass-Graft Surgery
New England Journal of Medicine. 1989 Apr 6; 320(14): 949-951.
Increased industry participation in university-based biomedical research has created greater opportunities for conflict of interest when any of the parties may benefit financially from the outcome of particular research. Presently there are no widely accepted conflict of interest guidelines for investigators conducting research, especially clinical trials, involving products with commercial value. The guidelines discussed here were developed voluntarily and agreed to unanimously by investigators in the Post Coronary Artery Bypass Graft Surgery Clinical Trial, a multicenter National Institutes of Health-sponsored study involving pharmaceuticals manufactured by three major American corporations. (KIE abstract)
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