Exposure of Patients to Human Immunodeficiency Virus Through the Transfusion of Blood Components That Test Antibody-Negative
Cumming, Paul D.
Wallace, Edward L.
Schorr, Julian B.
Dodd, Roger Y.
New England Journal of Medicine. 1989 Oct 5; 321(14): 941-946.
Using data from American Red Cross donors and human immunodeficiency virus (HIV) testing, the authors generated new information on the prevalence and incidence of HIV among blood donors. They describe the testing process, their conceptual approach, the "window period" between infection with HIV and seroconversion, accounting for human error, and their sources of data. Their findings led Cumming, et al. to conclude that the effectiveness of current testing of donated blood is between 92% and 97%, and that the odds of a patient contracting HIV from transfused blood are 1:153,000 per unit transfused. The authors end their report with a discussion of possible ways to further reduce the risk to transfusion recipients. Their suggestions include a general reduction in the number of units transfused per patient, less pooling of donated blood, and more sophisticated management of donor recruitment and blood collection. (KIE abstract)
Showing items related by title, author, creator and subject.
Exposure of Patients to Human Immunodeficiency Virus Through the Transfusion of Blood Components That Test Antibody-Negative Cumming, Paul D.; Wallace, Edward L.; Schorr, Julian B. and Dodd, Roger Y. (1989-10-05)
Estimated Risk of Transmission of the Human Immunodeficiency Virus by Screened Blood in the United States Lackritz, Eve M.; Satten, Glen A.; Aberle-Grasse, John; Dodd, Roger Y.; Raimondi, Vincent P.; Janssen, Robert S.; Lewis, W. Frank; Notari, Edward P.; Peterson, Lyle R. (1995-12-28)