Liver Transplantation in Patients With Alcoholic Cirrhosis: Selection Criteria and Rates of Survival and Relapse
Bird, George L.A.
O'Grady, John G.
Harvey, Felicity A.H.
Calne, Roy Y.
BMJ (British Medical Journal). 1990 Jul 7; 301(6742): 15-17.
Objective -- To evaluate the outcome of liver transplantation in patients with alcoholic cirrhosis with respect to selection criteria, survival, and evidence suggesting a return to harmful drinking...Main outcome measures -- Survival, rehabilitation, and clinical and laboratory evidence of a return to harmful drinking after transplantation...Results...The one year survival rate was 66%, and of the 18 patients surviving at least three months, 17 had been rehabilitated...Conclusions -- The survival and rehabilitation of patients who received transplants for alcoholic cirrhosis compared favourably with those of patients who received tranplants for cirrhosis of other aetiology. The criteria for selection for liver transplantation in patients with alcoholic cirrhosis should include recurrent complications related to severe portal hypertension despite maximum medical treatment in addition to a minimum period of six months of abstinence before transplantation.
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Liver Transplantation in Patients With Alcoholic Cirrhosis: Selection Criteria and Rates of Survival and Relapse Bird, George L.A.; O'Grady, John G.; Harvey, Felicity A.H.; Calne, Roy Y. and Williams, Roger (1990-07-07)