Are Clinical Trials a Cost-Effective Investment?
Detsky, Allan S.
JAMA. 1989 Oct 6; 262(13): 1795-1800.
Detsky describes the use of cost-effectiveness analysis to assess the economic attractiveness of clinical research. A theoretical model to measure cost-effectiveness was applied to a selected group of seven clinical trials performed over the last two decades. The model was used to consider the cost of performing a trial and the expected benefits to the health status of a target population before a trial is performed. The results then were compared with the cost-effectiveness ratios associated with performing conventional interventions of proved effectiveness. Results showed that the trials were a good investment, with lower dollar per life-year saved ratios than those associated with the proven interventions. Detsky sees the study results as being useful to policy makers who must set priorities when allocating health care funds in a climate of scarcity. (KIE abstract)
Biomedical Research; Biomedical Technologies; Clinical Trials; Costs and Benefits; Clinical Research; Economics; Evaluation; Financial Support; Health; Health Care; Health Status; Human Experimentation; Life; Methods; Morbidity; Mortality; Patient Care; Public Policy; Random Selection; Research; Resource Allocation; Scarcity; Statistics; Technology;
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