Ethics of Liver Transplantation With Living Donors
Singer, Peter A.
Whitington, Peter F.
New England Journal of Medicine. 1989 Aug 31; 321(9): 620-622.
Singer and six University of Chicago physicians describe their approach to the unique ethical aspects of liver transplantation with parents as living donors. The Chicago procedure, which at the time this article was written never had been performed, involves transplantation of a portion of a donor's liver to a noncritically ill infant with advanced liver disease, and is classed as innovative therapy. Singer, et al. describe the research ethics consultation before the research protocol was submitted to Chicago's institutional review board (IRB), the risks and benefits for recipients and donors, the selection of recipients and donors, and the consent process. They conclude that prospective research ethics consultation before IRB review provides an opportunity for public dialogue in assessing controversial research protocols like the liver transplantation procedure. (KIE abstract)
Clinical Ethics; Clinical Ethics Committees; Consent; Consultation; Disease; Donors; Ethics; Ethics Committees; Ethics Consultation; Family Members; Hospitals; Human Experimentation; Infants; Informed Consent; Institutional Policies; IRB; Livers; Living Donors; Liver Transplantation; Minors; Organ Donation; Organ Donors; Organ Transplantation; Parental Consent; Parents; Physicians; Prognosis; Research; Research Ethics; Research Ethics Committees; Review; Risks and Benefits; Selection for Treatment; Tissue Donation; Tissue Transplantation; Transplant Recipients; Transplantation;
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