Psychological Outcomes of Different Treatment Policies in Women With Early Breast Cancer Outside a Clinical Trial
BMJ (British Medical Journal). 1990 Sep 22; 301(6752): 575-580.
Objectives -- to assess outside a clinical trial the psychological outcome of different treatment policies in women with early breast cancer who underwent either mastectomy or breast conservation surgery depending on the surgeon's opinion or the patient's choice. To determine whether the extent of psychiatric morbidity reported in women who underwent breast conservation surgery was associated with their participation in a randomised clinical trial...Conclusions -- there is still no evidence that women with early breast cancer who undergo breast conservation surgery have less psychiatric morbidity after treatment than those who undergo mastectomy. Women who surrender autonomy for decision making by agreeing to participate in randomised clinical trials do not experience any different psychological, sexual, or social problems from those women who are treated for breast cancer outside a clinical trial.
Alternatives; Autonomy; Breast Cancer; Cancer; Clinical Trials; Consent; Decision Making; Disclosure; Drugs; Evaluation; Females; Human Experimentation; Informed Consent; Mastectomy; Morbidity; Patient Care; Patient Participation; Patients; Physicians; Psychological Stress; Random Selection; Research; Research Subjects; Sexuality; Social Problems; Surgery; Survey;
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