Prevalence of HIV Antibody and Pregnancy in Tayside, 1984-9: Background to Screening
Patel, Naren B.
Urquhart, George E.D.
Howie, Peter W.
BMJ (British Medical Journal). 1990 Sep 15; 301(6751): 518-520.
Objective -- to determine age specific prevalence of HIV antibody, incidence of pregnancy, and likelihood of detection and correct assignment to risk category by antenatal screening of women known to be positive for HIV antibody, from 1984-89. Design -- retrospective analysis of reproductive history and risk behaviour of women positive for HIV antibody and prediction of detection by screening on the basis of blood group samples, Guthrie tests, and rubella tests...Setting -- city of Dundee...Conclusion -- interpreting the results of antenatal screening programmes will be complex and will underestimate overall prevalence of HIV antibody among women; this will be exaggerated by strategies based on anonymous testing with Guthrie cards or on samples taken for rubella testing, which do not include women who have had an earlier loss of pregnancy. Only open testing with consent will permit satisfactory attribution to risk category and eliminate problems of retesting....
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