History of Organ Donation by Patients With Cardiac Death
DeVita, Michael A.
Snyder, James V.
Kennedy Institute of Ethics Journal. 1993 Jun; 3(2): 113-129.
When successful solid organ transplantation was initiated almost 40 years ago, its current success rate was not anticipated. But continuous efforts were undertaken to overcome the two major obstacles to success: injury caused by interrupting nutrient supply to the organ and rejection of the implanted organ by normal host defense mechanisms. Solutions have resulted from technological medical advances, but also from using organs from different sources. Each potential solution has raised ethical concerns and has variably resulted in social acclaim, censure, and apathy....While most organs came from donors declared dead by brain criteria, increasing shortage of donated organs has prompted a reexamination of prior restrictions of donor groups. Recently, organ procurement from donors with cardiac death has been reintrocduced in the United States. This practice had been mostly abandoned by the U.S. and some, though not all, other countries. Transplantation has been more successful using organs procured from heart-beating "brain dead" cadavers than organs from non-heart-beating cadavers. However recent advances have led to success rates with organs from non-heart-beating donors that may portend large increases in organ donation and procurement from this source.
Body Parts and Fluids; Brain; Brain Death; Cadavers; Cardiac Death; Consent; Death; Determination of Death; Donors; Family Members; Guidelines; Hearts; International Aspects; Kidneys; Organ Donation; Organ Donors; Organ Transplantation; Organ Procurement; Patients; Presumed Consent; Standards; Third Party Consent; Tissue Donation; Transplantation; Withholding Treatment;
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Development of the University of Pittsburgh Medical Center Policy for the Care of Terminally Ill Patients Who May Become Organ Donors After Death Following the Removal of Life Support DeVita, Michael A.; Snyder, James V. (1993-06)In the mid 1980s it was apparent that the need for organ donors exceeded those willing to donate. Some University of Pittsburgh Medical Center (UPMC) physicians initiated discussion of possible new organ donor categories including ...
Development of the University of Pittsburgh Medical Center Policy for the Care of Terminally Ill Patients Who May Become Organ Donors After Death Following the Removal of Life Support DeVita, Michael A.; Snyder, James V. (1993-06)