Psychological Issues in Genetic Testing for Breast Cancer Susceptibility
Archives of Internal Medicine. 1994 Mar 28; 154(6): 609-616.
In this article, we discuss psychological and behavioral issues relevant to genetic testing for breast cancer susceptibility. Recent findings in the field of breast cancer genetics are reviewed briefly, and a conceptual model for genetic testing for breast cancer susceptibility is presented. Three key psychological and behavioral issues are addressed: (1) ensuring informed consent for testing, (2) minimizing adverse psychological consequences, and (3) promoting breast cancer prevention and screening practices. These issues and accompanying recommendations are based on our comprehensive review of the literature on the psychological impact of genetic testing for traditional mendelian diseases, as well as our previous research on the psychological and behavioral impact of cancer risk notification and promoting adherence to cancer control regimens. Recommendations for research to evaluate pilot programs for genetic testing for breast cancer susceptibility are presented.
Age Factors; Breast Cancer; Cancer; Comprehension; Counseling; Carriers; Consent; Diagnosis; Disclosure; Discrimination; Employment; Family Members; Females; Genetic Counseling; Genetic Predisposition; Genetic Testing; Genetics; Genetic Screening; Health; Informed Consent; Insurance; Literature; Mass Screening; Medicine; Notification; Preventive Medicine; Research; Review; Risk; Risks and Benefits; Social Discrimination; Stigmatization; Surgery; Women's Health;
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