Neonatal Extracorporeal Membrane Oxygenation (ECMO): Clinical Trials and the Ethics of Evidence
Krauss, Alfred N.
Ross, Gail S.
Journal of Medical Ethics. 1993 Dec; 19(4): 212-218.
Neonatal extracorporeal membrane oxygenation (ECMO), a technology for the treatment of respiratory failure in newborns, is used as a case study to examine statistical and ethical aspects of clinical trials and to illustrate a proposed 'ethics of evidence', an approach to medical uncertainty within the context of contemporary biomedical ethics. Discussion includes the twofold aim of the ethics of evidence: to clarify the role of uncertainty and scientific evidence in medical decision-making, and to call attention to the need to confront the irreducible nature of uncertainty.
Alternatives; Biomedical Technologies; Clinical Trials; Communication; Control Groups; Consent; Ethics; Evaluation; Human Experimentation; Interdisciplinary Communication; Investigators; Mass Media; Minors; Mortality; Nature; Newborns; Parental Consent; Prognosis; Random Selection; Research; Research Design; Risks and Benefits; Statistics; Technology; Technology Assessment; Therapeutic Research; Treatment Outcome; Uncertainty;
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