Community-Equipoise and the Ethics of Randomized Clinical Trials
Bioethics. 1995 Apr; 9(2): 127-148.
This paper critically examines a particular strategy for resolving the central ethical dilemma associated with randomized clincial trials (RCTs) -- the "community equipoise" strategy (CE). The dilemma is that RCTs appear to violate a physician's duty to choose that therapy which there is most reason to believe is in the patient's best interest, randomizing patients even once evidence begins to favor one treatment. The community equipose strategy involves the suggestion that our judgment that neither treatment is to be preferred (that there obtains a state of "equipoise") is to be assessed according to a
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Gifford, Fred (1986-11)The assumption that randomized clinical trials are the best way to get reliable knowledge about the efficacy of treatments leads to conflict with the physician's therapeutic obligation to treat patients in the way that ...