Alternative Strategies to Randomized Clinical Trials
Van Peenen, P.F.D.
Horwitz, Ralph I.
JAMA: The Journal of the American Medical Association 1982 April 16; 247(15): 2100
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Problems in the Conduct and Analysis of Randomized Clinical Trials: Are We Getting the Right Answers to the Wrong Questions? Rabeneck, Linda; Viscoli, Catherine M.; Horwitz, Ralph I. (1992-03)To achieve the goal of validity, the randomized clinical trial has emerged as the scientific "gold standard" for evaluating therapies in clinical medicine. Regardless of how well randomized clinical trials are designed, however, ...