Referral of Patients With Cancer for Participation in Randomized Clinical Trials: Ethical Considerations
Levine, Robert J.
CA-A Cancer Journal for Clinicians 1986 March-April; 36(2): 95-99
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Levine, Robert J.; Dennison, David K. (1997-03)Ethical justification for starting a clinical trial requires at the outset an accurate statement of "no difference" regarding the two or more agents to be compared. This may be expressed as "theoretical equipoise" (no data ...