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Randomized Controlled Trials in Pregnancy: Scientific and Ethical Aspects. Exposure to Different Opioid Medications During Pregnancy in an Intra-Individual Comparison Unger, Annemarie; Jagsch, Reinhold; Jones, Hendree; Arria, Amelia; Leitich, Harald; Rohrmeister, Klaudia; Aschauer, Constantin; Winklbaur, Berndadette; Bäwert, Andjela; Fischer, Gabriele (2011-07)Chronic medical conditions such as opioid dependence require evidence-based treatment recommendations. However, pregnant women are under-represented in clinical trials. We describe the first within-subject comparison of ...