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• Clinical and Prophylactic Trials With Assured New Treatment for Those at Greater Risk: I. a Design Proposal 

  Finkelstein, Michael O.; Levin, Bruce; Robbins, Herbert (1996-05)

  OBJECTIVES: The accepted sine qua non for estimating the difference in efficacy between a new and a standard treatment is a randomized controlled clinical trial. Yet in some situations it is either practically or ...