Randomized Clinical Trials: Ethical Considerations
Levine, Robert J.
In: Edwards, Rem B.; Bittar, E. Edwards, eds. Advances in Bioethics: Bioethics for Medical Education. Greenwich, CT: JAI Press; 1999: 113-145.
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Levine, Robert J.; Dennison, David K. (1997-03)Ethical justification for starting a clinical trial requires at the outset an accurate statement of "no difference" regarding the two or more agents to be compared. This may be expressed as "theoretical equipoise" (no data ...