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Calcium Signaling in Cardiac Myocytes: Contributions from Mitochondria, Sodium-Calcium Exchanger, and Ryanodine Receptor Haviland, Sarah Suzanne (Georgetown University, 2013)This dissertation explores three critical players in the cardiac Ca2+ signaling pathway. First, I examined the role of mitochondria in Ca2+ signaling by generating a Ca2+ probe, mitycamE31Q, with 1.5μM affinity for ...
Stelfox, Henry Thomas; Chua, Grace; O'Rourke, Keith; Detsky, Allan S. (1998-01-08)BACKGROUND: Physicians' financial relationships with the pharmaceutical industry are controversial because such relationships may pose a conflict of interest. It is unknown to what extent industry support of medical education ...