Placebo-Controlled Trials Are Unethical in Clinical Hypertension Research
Halpern, Scott D.
Karlawish, Jason H. T.
Preston, Richard A.
Materson, Barry J.
Reda, Domenic J.
Archives of Internal Medicine 2000 November 13; 160(20): 3167- 3169
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Halpern, Scott D.; Karlawish, Jason H.T.; Berlin, Jesse A. (2002-07-17)Despite long-standing critiques of the conduct of underpowered clinical trials, the practice not only remains widespread, but also has garnered increasing support. Patients and healthy volunteers continue to participate ...