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Holcomb, John B; Weiskopf, Richard; Champion, Howard; Gould, Steven A; Sauer, R Michelle; Brasel, Karen; Bochicchio, Grant; Bulger, Eileen; Cotton, Bryan A; Davis, Daniel; Dutton, Richard; Hauser, Carl J; Hess, John R; Hides, George A; Knudson, Paula; MacKenzie, Ellen; McGinnis, Robert L; Michalek, Joel; Moore, Frederick A; Omert, Laurel; Pollock, Brad H; Tortella, Bartholomew; Sugarman, Jeremy; Schreiber, Martin A; Wade, Charles E (2011-02)Selection of study endpoints is one of the most important decisions in the design of effective clinical trials. Late mortality (e.g., 28 days) is an unambiguous endpoint, accepted by regulatory agencies, but it is viewed ...