A Problem for Achieving Informed Choice
La Caze, Adam
Theoretical Medicine and Bioethics 2008 August; 29(4): 255-265
Most agree that, if all else is equal, patients should be provided with enough information about proposed medical therapies to allow them to make an informed decision about what, if anything, they wish to receive. This is the principle of informed choice; it is closely related to the notion of informed consent. Contemporary clinical trials are analysed according to classical statistics. This paper puts forward the argument that classical statistics does not provide the right sort of information for informing choice. The notion of probability used by classical statistics is complex and difficult to communicate. Therapeutic decisions are best informed by statistical approaches that assign probabilities to hypotheses about the benefits and harms of therapies. Bayesian approaches to statistical inference provide such probabilities.
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Effect of Ethnicity, Gender and Drug Use History on Achieving High Rates of Affirmative Informed Consent for Genetics Research: Impact of Sharing With a National Repository Ray, Brenda; Jackson, Colin; Ducat, Elizabeth; Ho, Ann; Hamon, Sara; Kreek, Mary Jeanne (2011-06)Genetic research representative of the population is crucial to understanding the underlying causes of many diseases. In a prospective evaluation of informed consent we assessed the willingness of individuals of different ...