Expectations of Benefit in Early-Phase Clinical Trials: Implications for Assessing the Adequacy of Informed Consent
Weinfurt, Kevin P.
Seils, Damon M.
Tzeng, Janice P.
Compton, Kate L.
Sulmasy, Daniel P.
Astrow, Alan B.
Solarino, Nicholas A.
Schulman, Kevin A.
Meropol, Neal J.
Medical Decision Making 2008 July-August; 28(4): 575-581
Showing items related by title, author, creator and subject.
The Culture of Faith and Hope: Patients' Justifications for Their High Estimations of Expected Therapeutic Benefit When Enrolling in Early Phase Oncology Trials Sulmasy, Daniel P; Astrow, Alan B; He, M Kai; Seils, Damon M; Meropol, Neal J; Micco, Ellyn; Weinfurt, Kevin P (2010-08-01)BACKGROUND: Patients' estimates of their chances of therapeutic benefit from participation in early phase trials greatly exceed historical data. Ethicists worry that this therapeutic misestimation undermines the validity ...
Decisional Conflict Among Patients Who Accept or Decline Participation in Phase 1 Oncology Studies Flynn, Katheryn E.; Weinfurt, Kevin P.; Seils, Damon M.; Lin, Li; Burnett, Caroline B.; Schulman, Kevin A.; Meropol, Neal J. (2008-09)We compare decisional conflict among adults with advanced cancer who had accepted or declined participation in phase I cancer clinical trials. Respondents completed a 121-item questionnaire that included the Decisional ...
Patient Expectations of Benefit From Phase I Clinical Trials: Linguistic Considerations in Diagnosing a Therapeutic Misconception Weinfurt, K.P.; Sulmasy, D.P.; Schulman, K.A.; Meropol, N.J. (2003)The ethical treatment of cancer patients participating in clinical trials requires that patients are well-informed about the potential benefits and risks associated with participation. When patients enrolled in phase I ...