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dc.creatorLecouturier, Janen
dc.creatorRodgers, Helenen
dc.creatorFord, Gary A.en
dc.creatorRapley, Timen
dc.creatorStobbart, Lynneen
dc.creatorLouw, Stephen J.en
dc.creatorMurtagh, Madeleine J.en
dc.date.accessioned2016-01-08T23:15:14Zen
dc.date.available2016-01-08T23:15:14Zen
dc.date.created2008-04-29en
dc.date.issued2008-04-29en
dc.identifierdoi:10.1186/1472-6939-9-9en
dc.identifier.bibliographicCitationBMC Medical Ethics [electronic] 2008 April 29; 9:9. 9 p. Accessed: http://www.biomedcentral.com/1472-6939/9/9 [2008 June 22]en
dc.identifier.urihttp://worldcatlibraries.org/registry/gateway?version=1.0&url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&atitle=Clinical+research+without+consent+in+adults+in+the+emergency+setting:+review+of+patient+and+public+views&title=BMC+Medical+Ethics+&volume=&issue=&date=2008-04&au=Lecouturier,+Jan;+Rodgers,+Helen;+Ford,+Gary+A.;+Rapley,+Tim;+Stobbart,+Lynne;+Louw,+Stephen+J.;+Murtagh,+Madeleine+J.en
dc.identifier.urihttp://dx.doi.org/10.1186/1472-6939-9-9en
dc.identifier.urihttp://timetravel.mementoweb.org/memento/2008/http://www.biomedcentral.com/1472-6939/9/9en
dc.identifier.urihttp://hdl.handle.net/10822/957553en
dc.description.abstractBackground: In emergency research, obtaining informed consent can be problematic. Research to develop and improve treatments for patients admitted to hospital with life-threatening and debilitating conditions is much needed yet the issue of research without consent (RWC) raises concerns about unethical practices and the loss of individual autonomy. Consistent with the policy and practice turn towards greater patient and public involvement in health care decisions, in the US, Canada and EU, guidelines and legislation implemented to protect patients and facilitate acute research with adults who are unable to give consent have been developed with little involvement of the lay public. This paper reviews research examining public opinion regarding RWC for research in emergency situations, and whether the rules and regulations permitting research of this kind are in accordance with the views of those who ultimately may be the most affected. Methods: Seven electronic databases were searched: Medline, Embase, CINAHL, Cochrane Database of Systematic Reviews, Philosopher's Index, Age Info, PsychInfo, Sociological Abstracts and Web of Science. Only those articles pertaining to the views of the public in the US, Canada and EU member states were included. Opinion pieces and those not published in English were excluded. Results: Considering the wealth of literature on the perspectives of professionals, there was relatively little information about public attitudes. Twelve studies employing a range of research methods were identified. In five of the six questionnaire surveys around half the sample did not agree generally with RWC, though paradoxically, a higher percentage would personally take part in such a study. Unfortunately most of the studies were not designed to investigate individuals' views in any depth. There also appears to be a level of mistrust of medical research and some patients were more likely to accept an experimental treatment 'outside' of a research protocol. Conclusion: There are too few data to evaluate whether the rules and regulations permitting RWC protects ? or is acceptable to ? the public. However, any attempts to engage the public should take place in the context of findings from further basic research to attend to the apparently paradoxical findings of some of the current surveys.en
dc.formatArticleen
dc.languageenen
dc.sourceeweb:316130en
dc.subjectAdultsen
dc.subjectAttitudesen
dc.subjectAutonomyen
dc.subjectClinical Researchen
dc.subjectConsenten
dc.subjectDatabasesen
dc.subjectGuidelinesen
dc.subjectHealthen
dc.subjectHealth Careen
dc.subjectInformed Consenten
dc.subjectLegislationen
dc.subjectLifeen
dc.subjectLiteratureen
dc.subjectMethodsen
dc.subjectMedical Researchen
dc.subjectPatientsen
dc.subjectPublic Opinionen
dc.subjectResearchen
dc.subjectReviewen
dc.subjectScienceen
dc.subjectSurveysen
dc.subject.classificationInformed Consent or Human Experimentationen
dc.subject.classificationInternational and Political Dimensions of Biology and Medicineen
dc.subject.classificationResearch on Special Populationsen
dc.titleClinical Research Without Consent in Adults in the Emergency Setting: Review of Patient and Public Viewsen
dc.provenanceCitation prepared by the Library and Information Services group of the Kennedy Institute of Ethics, Georgetown University for the ETHXWeb database.en
dc.provenanceCitation migrated from OpenText LiveLink Discovery Server database named EWEB hosted by the Bioethics Research Library to the DSpace collection EthxWeb hosted by DigitalGeorgetown.en


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