Comment Regarding Benefit in Phase 1 Oncology Trials
Clinical Trials 2008; 5(6): 626; discussion 630
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The Culture of Faith and Hope: Patients' Justifications for Their High Estimations of Expected Therapeutic Benefit When Enrolling in Early Phase Oncology Trials Sulmasy, Daniel P; Astrow, Alan B; He, M Kai; Seils, Damon M; Meropol, Neal J; Micco, Ellyn; Weinfurt, Kevin P (2010-08-01)BACKGROUND: Patients' estimates of their chances of therapeutic benefit from participation in early phase trials greatly exceed historical data. Ethicists worry that this therapeutic misestimation undermines the validity ...