The Therapeutic Misconception at 25: Treatment, Research, and Confusion
Hastings Center Report 2007 November-December; 37(6): 36-42
"Therapeutic misconception" has been misconstrued, and some of the newer, mistaken interpretations are troublesome. They exaggerate the distinction between research and treatment revealing problems in the foundations of research ethics and possibly weakening informed consent.
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Elements of style: consent form language and the therapeutic misconception in phase 1 gene transfer trials Kimmelman, Jonathan; Levenstadt, Aaron (2005-04)The therapeutic misconception arises wherever human subjects misinterpret the primary purpose of a clinical trial as therapeutic. Such misconceptions are particularly prevalent in trials involving severely ill subjects or ...
Appelbaum, Paul S.; Lidz, Charles W.; Miller, Franklin G.; Kimmelman, Jonathan (2008-03)
Confronting the issues of therapeutic misconception enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders Arkin, Lisa M.; Sondhi, Dolan; Worgall, Stefan; Suh, Lily Hyon K.; Hackett, Neil R.; Kaminsky, Stephen M.; Hosain, Syed A.; Souweidane, Mark M.; Kaplitt, Michael G.; Dyke, Jonathan P.; Heier, Linda A.; Ballon, Douglas J.; Shungu, Dikoma C.; Wisniewski, Kry (2005-09)Genetic medicine-based therapies have unlocked the potential for ameliorating diseases previously considered inevitably fatal. Inherent in the clinical trials of genetic medicines are ethical issues of therapeutic ...