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• When Ethics Constrains Clinical Research: Trial Design of Control Arms in "Greater Than Minimal Risk" Pediatric Trials 

  de Melo-Martín, Inmaculada; Sondhi, Dolan; Crystal, Ronald G (2011-09)

  For more than three decades clinical research in the United States has been explicitly guided by the idea that ethical considerations must be central to research design and practice. In spite of the centrality of this idea, ...