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dc.creatorRidker, Paul M.en
dc.creatorTorres, Joseen
dc.date.accessioned2016-01-08T23:32:57Zen
dc.date.available2016-01-08T23:32:57Zen
dc.date.created2006-05-17en
dc.date.issued2006-05-17en
dc.identifierdoi:10.1001/jama.295.19.2270en
dc.identifier.bibliographicCitationJAMA: The Journal of the American Medical Association 2006 May 17; 295(19): 2270-2274en
dc.identifier.urihttp://worldcatlibraries.org/registry/gateway?version=1.0&url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&atitle=Reported+outcomes+in+major+cardiovascular+clinical+trials+funded+by+for-profit+and+not-for-profit+organization:+2000-2005&title=JAMA:+The+Journal+of+the+American+Medical+Association+&volume=295&issue=19&date=2006-05&au=Ridker,+Paul+M.;+Torres,+Joseen
dc.identifier.urihttp://dx.doi.org/10.1001/jama.295.19.2270en
dc.identifier.urihttp://hdl.handle.net/10822/972553en
dc.description.abstractCONTEXT: In surveys based on data available prior to 2000, clinical trials funded by for-profit organizations appeared more likely to report positive findings than those funded by not-for-profit organizations. Whether this situation has changed over the past 5 years or whether similar effects are present among jointly funded trials is unknown. OBJECTIVE: To determine in contemporary randomized cardiovascular trials the association between funding source and the likelihood of reporting positive findings. DESIGN: We reviewed 324 consecutive superiority trials of cardiovascular medicine published between January 1, 2000, and July 30, 2005, in JAMA, The Lancet, and the New England Journal of Medicine. MAIN OUTCOME MEASURE: The proportion of trials favoring newer treatments over the standard of care was evaluated by funding source. RESULTS: Of the 324 superiority trials, 21 cited no funding source. Of the 104 trials funded solely by not-for-profit organizations, 51 (49%) reported evidence significantly favoring newer treatments over the standard of care, whereas 53 (51%) did not (P = .80). By contrast, 92 (67.2%) of 137 trials funded solely by for-profit organizations favored newer treatments over standard of care (Pen
dc.formatArticleen
dc.languageenen
dc.sourceeweb:296515en
dc.subjectClinical Trialsen
dc.subjectMedicineen
dc.subjectOrganizationsen
dc.subjectReportingen
dc.subjectSurveysen
dc.subject.classificationProfessional-Professional Relationshipen
dc.subject.classificationDrugs and Drug Industryen
dc.subject.classificationHuman Experimentationen
dc.subject.classificationScientific Research Ethicsen
dc.subject.classificationEconomics of Health Careen
dc.titleReported Outcomes in Major Cardiovascular Clinical Trials Funded by for-Profit and Not-for-Profit Organization: 2000-2005en
dc.provenanceCitation prepared by the Library and Information Services group of the Kennedy Institute of Ethics, Georgetown University for the ETHXWeb database.en
dc.provenanceCitation migrated from OpenText LiveLink Discovery Server database named EWEB hosted by the Bioethics Research Library to the DSpace collection EthxWeb hosted by DigitalGeorgetown.en


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