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dc.creatorWolthers, O.D.en
dc.date.accessioned2016-01-08T23:33:08Zen
dc.date.available2016-01-08T23:33:08Zen
dc.date.created2006-05en
dc.date.issued2006-05en
dc.identifier.bibliographicCitationJournal of Medical Ethics 2006 May; 32(5): 292-297en
dc.identifier.urihttp://worldcatlibraries.org/registry/gateway?version=1.0&url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&atitle=A+questionaire+on+factors+influencing+children's+assent+and+dissent+to+non-therapeutic+research&title=Journal+of+Medical+Ethics+&volume=32&issue=5&date=2006-05&au=Wolthers,+O.D.en
dc.identifier.urihttp://hdl.handle.net/10822/972865en
dc.description.abstractBACKGROUND: Knowledge about assent or dissent of children to non-therapeutic research is poor. OBJECTIVES: To assess sociodemographic characteristics in healthy children and adolescents who were invited to participate in non-therapeutic research, to evaluate their motives for assent or dissent and their understanding of the information given. METHODS: A total of 1281 healthy children and adolescents six to sixteen years of age were invited to participate in a non-therapeutic study and a questionnaire. RESULTS: Assenting children were motivated by a desire to help sick children (n = 638, 98%) and to gain experience with participating in a research study (n = 503, 82%). Dissenting children made their decision because of worries about having a blood (n = 193, 46%) or a urine sample (n = 94, 26%) taken or because of worries about a doctor's examination (n = 136, 33%). Fewer children in the assent group (n = 166, 25%) than in the dissent group (136, 33%) worried about the doctor's examination (p = 0.01). In the assent and dissent group, 568 (86%) and 343 (85%) children, respectively, said they were able to understand some or all of the written information (p = 0.42), and 650 (97%) and 330 (98%), respectively, were able to understand some or all of the verbal information (p = 0.07). CONCLUSIONS: Sociodemographic characteristics may not influence healthy children's decision to volunteer for non-therapeutic research. Assenting children have altruistic and educational motives, whereas worries about procedures may cause children to dissent. A great majority of school children and adolescents feel capable of understanding and giving assent or dissent to non-therapeutic research.en
dc.formatArticleen
dc.languageenen
dc.sourceeweb:296138en
dc.subjectAdolescentsen
dc.subjectBlooden
dc.subjectChildrenen
dc.subjectDissenten
dc.subjectKnowledgeen
dc.subjectMethodsen
dc.subjectResearchen
dc.subjectTherapeutic Researchen
dc.subject.classificationInformed Consent or Human Experimentationen
dc.subject.classificationResearch on Newborns and Minorsen
dc.subject.classificationMinors / Parental Consenten
dc.titleA Questionaire on Factors Influencing Children's Assent and Dissent to Non-Therapeutic Researchen
dc.provenanceCitation prepared by the Library and Information Services group of the Kennedy Institute of Ethics, Georgetown University for the ETHXWeb database.en
dc.provenanceCitation migrated from OpenText LiveLink Discovery Server database named EWEB hosted by the Bioethics Research Library to the DSpace collection EthxWeb hosted by DigitalGeorgetown.en


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