When (Not) to Stop a Clinical Trial for Benefit
Pocock, Stuart J.
JAMA: The Journal of the American Medical Association 2005 November 2; 294(17): 2228-2230
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Pocock, Stuart J. (1992-07-25)This article focuses on the ethical dilemma of when to stop a clinical trial and places statistical stopping rules in the context of such ethical decision making. Other issues include the organisation of data monitoring ...